KNOXVILLE, Tenn. - Tyler Smith hit a layup with 4.2 seconds to play and No. 8 Tennessee handed No. 16 Mississippi its first loss of the season, 85-83 on Wednesday night.

Tennessee's JaJuan Smith (2) celebrates with teammates Tyler Smith and others after Tyler hit the game-winning basket during the second half of a basketball game against Mississippi ,Wednesday, Jan. 9, 2008, in Knoxville, Tenn. Both Smith's scored 21 points as Tennessee won, 85-83. (AP Photo/Wade Payne)

With the score tied at 83 in the Southeastern Conference opener for both teams, Ole Miss missed several shots but grabbed four rebounds before JaJuan Smith fouled Kenny Williams with 31 seconds left.

JaJuan Smith rebounded the missed free throw and the Vols (13-1) moved the ball around until Tyler Smith's layup.

The Rebels (13-1), who entered the game as one of Division I's last six undefeated teams, were unable to get off a final shot.

Tennessee took a 72-60 lead with 11 minutes left on a free throw by Tyler Smith. But Ole Miss chipped away at that lead with a 23-7 run that ended on a jumper by Eniel Polynice that put the Rebels up 83-79 with 2:22 left.

Wayne Chism and Tyler Smith hit consecutive jump shots to tie the game at 83.

Tyler Smith and JaJuan Smith both had 21 points for Tennessee, while Chris Lofton finished with 10. Chism grabbed eight rebounds.

Chris Warren led Mississippi with 24 points, while Polynice had 20 and Dwayne Curtis finished with 15 points and 13 rebounds.

Three-pointers by Lofton and JaJuan Smith put Tennessee up 38-30. Ole Miss responded with a 9-0 run to take a one-point lead on a basket by Curtis.

Tennessee shot 47.1 percent from the field, while the Rebels hit 43.7 percent. The Vols went 46.2 percent from behind the arc, while Ole Miss hit 32 percent of its 3-point attempts.